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10.21037/apm.2019.01.05 12 LazicR.GabricN.DekarisI.BosnarD.Boban-BlagaicA.SikiricP

Inadequate sleep disrupts the brains glymphatic system, which clears toxins and waste from the central nervous system

Our findings confirm that longer diabetes duration is associated with a lower glycaemic response to GLP-1 RAs [3, 6, 16], probably due to declining beta cell function, as intact insulin secretion is necessary for a robust glycaemic response to this drug class [1, 3]